Schwartz A M, Homer M J, McCauley R G
AJR Am J Roentgenol. 1979 Jan;132(1):81-5. doi: 10.2214/ajr.132.1.81.
Two patients with Gaucher's disease and radiographic findings in the spine similar to sickle cell hemoglobinopathy are reported, making a total of four known patients with Gaucher's disease who have these steplike vertebral endplate deformities. Serial films of a patient having Gaucher's disease compared with patients having sickle cell hemoglobinopathy suggest that different events lead to formation of the vertebral deformities. In Gaucher's disease, there is an initial collapse of the entire vertebral body with subsequent growth recovery peripherally. In sickle cell hemoglobinopathy, the endplate deformity is nontraumatic and is caused by an underlying growth arrest.
本文报告了两名患有戈谢病且脊柱影像学表现类似于镰状细胞血红蛋白病的患者，至此共有四名已知患有戈谢病且有这些阶梯状椎体终板畸形的患者。将一名戈谢病患者的系列X光片与镰状细胞血红蛋白病患者的X光片进行比较，结果表明导致椎体畸形形成的病因不同。在戈谢病中，整个椎体最初会塌陷，随后周边会出现生长恢复。在镰状细胞血红蛋白病中，终板畸形并非由创伤引起，而是由潜在的生长停滞所致。
