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阿肯色州儿童血铅筛查:给医疗服务提供者的建议

Childhood blood lead screening in Arkansas: recommendations for health care providers.

作者信息

West R

机构信息

Division of Child and Adolescent Health, Arkansas Department of Health, Little Rock, USA.

出版信息

J Ark Med Soc. 1999 May;95(12):532-7.

Abstract

Multiple studies documenting regional differences in prevalence of elevated blood lead levels suggest that children are not at equal risk for lead exposure. In late 1997, the Centers for Disease Control and Prevention (CDC) published guidelines to help states and communities make decisions regarding screening practices. To apply these guidelines to Arkansas Department of Health blood lead data for the 8,883 screens completed in state fiscal year 1997, along with 1990 Census Bureau housing and poverty statistics, were compiled and reviewed. Based upon CDC criteria and other available information, conservative recommendations for blood lead screening are presented for each county in the state. Lead toxicity in children remains a significant public health concern in certain regions of the country. Between 1991-1994, it was estimated about 930,000 U.S. children one to five years old had lead levels > or = 10 micrograms/dL. Children most at risk include minorities, those residing in large central cities, and those living in poverty. Blood lead levels (BLL's) as low as 10 micrograms/dL have been linked with possible IQ deficits as well as learning and behavior problems. To date, no study has demonstrated benefit from reduction of blood lead levels in the 10-24 micrograms/dL range. Nonetheless, in 1991 the Centers for Disease Control and Prevention (CDC) published guidelines for screening and followup designed to detect lead levels this low, presumably in order to prevent additional exposure and perhaps shorten the duration of toxicity. These guidelines essentially called for universal screening of one- and two-year old children regardless of socioeconomic status or previous population-based results of lead screening in their locale. [table: see text] Since release of the controversial 1991 guidelines, several reports of lead toxicity prevalence surveys from diverse communities have demonstrated extreme variation in the magnitude of the problem. For example, in 1994 only 0.6% of Alaska Medicaid recipients six years or younger had lead levels > or = 10 micrograms/dL, with the highest being 11 micrograms/dL.

摘要

多项记录血铅水平升高患病率存在地区差异的研究表明,儿童面临铅暴露的风险并不相同。1997年末,疾病控制与预防中心(CDC)发布了指导方针,以帮助各州和社区就筛查措施做出决策。为了将这些指导方针应用于阿肯色州卫生部1997财年完成的8883次血铅筛查数据,同时还收集并审查了1990年人口普查局的住房和贫困统计数据。根据疾病控制与预防中心的标准及其他可用信息,针对该州每个县提出了保守的血铅筛查建议。儿童铅中毒在该国某些地区仍然是一个重大的公共卫生问题。在1991年至1994年期间,据估计约有93万美国1至5岁儿童的血铅水平≥10微克/分升。风险最高的儿童包括少数族裔、居住在大型中心城市的儿童以及生活贫困的儿童。低至10微克/分升的血铅水平(BLL)与可能的智商缺陷以及学习和行为问题有关。迄今为止,尚无研究表明降低10至24微克/分升范围内的血铅水平有何益处。尽管如此,1991年疾病控制与预防中心(CDC)发布了筛查和随访指导方针,旨在检测如此低的铅水平,大概是为了防止进一步暴露并可能缩短中毒持续时间。这些指导方针基本上要求对1岁和2岁儿童进行普遍筛查,无论其社会经济地位或所在地区以往基于人群的铅筛查结果如何。[表格:见正文]自1991年有争议的指导方针发布以来,来自不同社区的几份铅中毒患病率调查报告显示,该问题的严重程度存在极大差异。例如,1994年,阿拉斯加6岁及以下医疗补助受助人中只有0.6%的血铅水平≥10微克/分升,最高为11微克/分升。

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