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A relative power table for nested matched case-control studies.

作者信息

Pang D

机构信息

Institute of Occupational Health, University of Birmingham, Edgbaston, UK.

出版信息

Occup Environ Med. 1999 Jan;56(1):67-9. doi: 10.1136/oem.56.1.67.

Abstract

OBJECTIVE

To calculate relative powers for nested case-control studies for different values of both relative risk and numbers of controls per case, given a fixed number of cases available for analysis.

METHODS

Algebraic and numerical methods.

RESULTS

In nested case-control studies, statistical power is a function of relative risk, rarity of exposure, number of case-control sets, and the number of controls per case.

CONCLUSION

The dictum that sufficient power will be obtained in a nested case-control study by selecting only four controls per case cannot be sustained. Appropriate numbers need to be calculated for specific studies.

摘要

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