Atarashi H
First Department of Internal Medicine, Nippon Medical School, Tokyo.
J Cardiol. 1999 Mar;33 Suppl 1:53-7.
A number of experimental studies have been proposed to show that reentry is an important electrophysiological mechanism related to the development of atrial fibrillation. The beginning of the computer era enabled us to analyze the atrial activation during atrial fibrillation. The results of these studies were fascinating and allow for the development of theories and speculations on the mechanism of atrial fibrillation. Sophisticated computer techniques also allowed Moe to simulate atrial electrical activity during atrial fibrillation, and their team formulated so-called multiple wavelet theory which was subsequently supported by experimental evidence. Spiral wave for ventricular fibrillation was also proposed for the atrial activation mechanism during atrial fibrillation in the experimental model. The evidence available at the moment warrants the statement that atrial fibrillation is caused by multiple wavelet reentry. These studies will allow a better understanding of the relative importance of wavelength and structural inhomogeneities in the genesis of atrial fibrillation.
许多实验研究表明，折返是与房颤发生相关的重要电生理机制。计算机时代的开启使我们能够分析房颤时的心房激动情况。这些研究结果令人着迷，为房颤机制的理论和推测发展提供了依据。先进的计算机技术也使莫伊能够模拟房颤时的心房电活动，其团队提出了所谓的多小波理论，该理论随后得到了实验证据的支持。在实验模型中，还针对房颤时的心房激动机制提出了室颤的螺旋波。目前可得的证据支持房颤是由多小波折返引起的这一说法。这些研究将有助于更好地理解波长和结构不均匀性在房颤发生中的相对重要性。
