Naruse S, Odake G, Yamaki T, Toyama M
No Shinkei Geka. 1976 Nov;4(11):1085-93.
Two cases of intracranial invasion of the ethmoid cancer were reported. With additional six cases reported in Japan, the precise clinical course and pathophysiological findings of the disease were reviewed, and the following several points became clear; 1) The incidence of the ethmoid cancer was rare. 2) These were divided into main groups according to the onset of intracranial signs, such as the frontal lobe symptoms and I-VII cranial nerve involvement. The first group showed the intracranial symptoms early, and the second group late. 3) The tumor invaded the cranial cavity along the perineural sheeth of each cranial nerve mainly. 4) It was very difficult to identify the paranasal sinus of origin after invading the cranial cavity. 5) The prognosis was extremely poor. All cases were died within one and half year.
报告了2例筛窦癌颅内侵犯的病例。结合日本报道的另外6例病例,对该病的精确临床病程和病理生理学发现进行了回顾,明确了以下几点:1)筛窦癌的发病率很低。2)根据颅内体征的出现情况,可分为主要几组,如额叶症状和第I - VII对脑神经受累。第一组较早出现颅内症状,第二组较晚出现。3)肿瘤主要沿各脑神经的神经鞘膜侵入颅腔。4)肿瘤侵入颅腔后,很难确定其起源的鼻窦。5)预后极差。所有病例均在一年半内死亡。