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“可避免”死亡率的差异:发病率差异的一种反映?

Variations in 'avoidable' mortality: a reflection of variations in incidence?

作者信息

Treurniet H F, Looman C W, van der Maas P J, Mackenbach J P

机构信息

Erasmus University, Department of Public Health, Rotterdam, The Netherlands.

出版信息

Int J Epidemiol. 1999 Apr;28(2):225-32. doi: 10.1093/ije/28.2.225.

Abstract

BACKGROUND

Variations in 'avoidable' mortality may reflect variations in the quality of care, but they may also be due to variations in incidence or severity of diseases. We studied the association between regional variations in 'avoidable' mortality and variations in disease incidence. For a selection of conditions we also analysed whether the proportion of in-hospital deaths can explain the regional variations in incidence-adjusted mortality.

METHODS

Relative risks for mortality, incidence, incidence-adjusted mortality and in-hospital mortality (1984-1994) were calculated by log-linear regression. Linear regression was used to examine the relationship between mortality and incidence on the one hand, and between incidence-adjusted mortality and in-hospital mortality on the other.

RESULTS

Significant regional mortality variations were found for cervical cancer, cancer of the testis, hypertensive and cerebrovascular disease, influenza/pneumonia, cholecystitis/lithiasis, perinatal causes and congenital cardiovascular anomalies. Regional mortality differences in general were only partly accounted for by incidence variations. The only exception was cervical cancer, which no longer showed significant variations after adjustment for incidence. The contribution of inhospital mortality variations to total cause-specific mortality variations varied between conditions: the highest percentage of explained variance was found for mortality from CVA (60.1%) and appendicitis (29.2%).

CONCLUSIONS

Incidence data are a worthy addition to studies on 'avoidable' mortality. It is to be expected that the incidence-adjusted mortality rates are more sensitive for quality-of-care variations than the 'crude' mortality variations. Nevertheless, further research at the individual level is needed to identify possible deficiencies in health care delivery.

摘要

背景

“可避免”死亡率的差异可能反映了医疗质量的差异,但也可能是由于疾病发病率或严重程度的差异。我们研究了“可避免”死亡率的地区差异与疾病发病率差异之间的关联。对于某些选定的疾病,我们还分析了住院死亡比例是否能够解释发病率调整后死亡率的地区差异。

方法

通过对数线性回归计算死亡率、发病率、发病率调整后死亡率和住院死亡率(1984 - 1994年)的相对风险。一方面,使用线性回归来检验死亡率与发病率之间的关系;另一方面,检验发病率调整后死亡率与住院死亡率之间的关系。

结果

发现宫颈癌、睾丸癌、高血压和脑血管疾病、流感/肺炎、胆囊炎/结石、围产期病因以及先天性心血管异常存在显著的地区死亡率差异。总体而言,地区死亡率差异仅部分由发病率差异所解释。唯一的例外是宫颈癌,在对发病率进行调整后不再显示出显著差异。住院死亡率差异对特定病因总死亡率差异的贡献因疾病而异:卒中相关性死亡率(CVA)和阑尾炎死亡率的解释方差百分比最高,分别为60.1%和29.2%。

结论

发病率数据是“可避免”死亡率研究的一个有价值的补充。可以预期,发病率调整后的死亡率比“粗”死亡率对医疗质量差异更敏感。然而,需要在个体层面进行进一步研究,以确定医疗服务提供中可能存在的不足。

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