Finogenova S A, Gindilis V M
Genetika. 1976;12(9):128-38.
A method is described increasing the reliability of twin zygosity diagnosis in cases when the possibility of using a large number of mendelian markers is restricted. The method is based on the determination of generalized index of dermatoglyphic differences between members of twin pair for 18 characteris of finger and palm dermatoglyphics and on principles of multivariate genetic analysis, which is worked out to determine the degree of heritability of multifactorial character and to study the structure of hereditary predisposition to multifactorial diseases. The efficiency of the method with respect to determinating the type of twin zygosity is approximately equivalent to the efficiency of using 5--6 mendelian marker systems.
本文描述了一种方法，该方法在使用大量孟德尔标记的可能性受到限制的情况下，可提高双胞胎合子性诊断的可靠性。该方法基于对双胞胎手指和手掌皮纹的18个特征的皮纹差异广义指数的测定，以及多变量遗传分析原理，该原理用于确定多因素性状的遗传度，并研究多因素疾病遗传易感性的结构。该方法在确定双胞胎合子性类型方面的效率大约等同于使用5 - 6个孟德尔标记系统的效率。
