毛萼香茶菜中的二萜类化合物。

Diterpenoids from isodon eriocalyx.

作者信息

Chen SN, Yue JM, Chen SY, Lin ZW, Qin GW, Sun HD, Chen YZ

机构信息

Shanghai Institute of Materia Medica, Academia Sinica, Shanghai 200031, People's Republic of China, Laboratory of Phytochemistry, Kunming Institute of Botany, Academia Sinica, Kunming 650204, People's Republic of China, and Department of.

出版信息

J Nat Prod. 1999 May;62(5):782-4. doi: 10.1021/np9804278.

DOI:10.1021/np9804278

PMID:10346971

Abstract

Three new diterpenoids, eriocalyxins C-E (1-3), were isolated from Isodon eriocalyx. Their structures were elucidated as 6beta-hydroxy-15beta-acetoxy-3alpha,20-epoxy-16beta, 17-epoxy-ent-kaur-1,7-dione (1), 1alpha,7beta-dihydroxy-6beta, 15beta-diacetoxy-7,20-epoxy-ent-kaur-16-ene (2), and 15beta-acetoxy-1,6-dioxo-6,7-seco-ent-kaur-2,16-dien-7,20-olide (3), respectively, by means of spectroscopic methods, including one- and two-dimensional NMR techniques.

摘要

从毛萼香茶菜（Isodon eriocalyx）中分离出了三种新的二萜类化合物，毛萼香茶菜素C - E（1 - 3）。通过光谱方法，包括一维和二维核磁共振技术，分别确定它们的结构为6β - 羟基 - 15β - 乙酰氧基 - 3α,20 - 环氧 - 16β,17 - 环氧 - 对映 - 贝壳杉 - 1,7 - 二酮（1）、1α,7β - 二羟基 - 6β,15β - 二乙酰氧基 - 7,20 - 环氧 - 对映 - 贝壳杉 - 16 - 烯（2）和15β - 乙酰氧基 - 1,6 - 二氧代 - 6,7 - 裂环 - 对映 - 贝壳杉 - 2,16 - 二烯 - 7,20 - 内酯（3）。