de Fijter W M, Roumen R M, Lybeert M L, de Munck D R, Luiten E J
Afd. Algemene Chirurgie, Sint Joseph Ziekenhuis, Veldhoven.
Ned Tijdschr Geneeskd. 1999 Apr 17;143(16):833-6.
Radiation therapy for breast cancer can cause pulmonary damage. This was diagnosed in two patients aged 75 and 57 years respectively. They had different types of radiation pneumonitis. The first patient presented with a so-called bronchiolitis obliterans organizing pneumonia (BOOP), four months after radiation therapy. Characteristic in BOOP are the bilateral and migrating lung infiltrates that are distributed predominantly in the middle and lower lung zones. The second patient developed a pneumonitis that classically was confined to the area of irradiation four months after radiation therapy. The two types of radiation pneumonitis can be treated successfully with corticosteroids. If symptomatic radiation pneumonitis is diagnosed early it can be treated well and than has a good prognosis.
乳腺癌放疗可导致肺部损伤。分别在两名75岁和57岁的患者中诊断出这种情况。他们患有不同类型的放射性肺炎。第一名患者在放疗四个月后出现所谓的闭塞性细支气管炎伴机化性肺炎（BOOP）。BOOP的特征是双侧、游走性肺部浸润，主要分布在肺中、下区域。第二名患者在放疗四个月后出现典型的局限于照射区域的肺炎。这两种类型的放射性肺炎可用皮质类固醇成功治疗。如果早期诊断出有症状的放射性肺炎，就可以得到很好的治疗，预后良好。
