使用氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）和六甲基丙烯胺肟单光子发射计算机断层扫描（HMPAO-SPECT）对脑室周围结节性异位进行功能成像。

Functional imaging in periventricular nodular heterotopia with the use of FDG-PET and HMPAO-SPECT.

作者信息

Morioka T, Nishio S, Sasaki M, Yoshida T, Kuwabara Y, Ohta M, Fukui M

机构信息

Department of Neurosurgery, Neurological Institute, Faculty of Medicine, Kyusyu University, Japan.

出版信息

Neurosurg Rev. 1999;22(1):41-4. doi: 10.1007/s101430050007.

DOI:10.1007/s101430050007

PMID:10348206

Abstract

We analyzed the interictal [18F]fluoro-2-deoxy-D-glucose positron emission tomography (FGD-PET) and single photon emission computed tomography with technetium-99m-hexamethyl-propyleneamine oxime (HMPAO-SPECT) in two epileptic patients with periventricular nodular heterotopia (PNH). In both cases, we found both the glucose metabolism and the perfusion of PNH to be almost identical to those of the normal cerebral cortex. The metabolic activity and perfusion in the heterotopic gray matter in a subependymal white matter area probably represent the glucose metabolism and perfusion of the abnormally located gray matter rather than a subclinical ictal phenomenon. FDG-PET and HMPAO-SPECT were thus found to be a useful complement to magnetic resonance imaging in the evaluation of PNH.

摘要

我们分析了2例患有室管膜下结节性异位（PNH）的癫痫患者的发作间期[18F]氟代脱氧葡萄糖正电子发射断层扫描（FGD-PET）及锝-99m-六甲基丙烯胺肟单光子发射计算机断层扫描（HMPAO-SPECT）。在这两例患者中，我们发现PNH的葡萄糖代谢及灌注情况与正常脑皮质几乎相同。室管膜下白质区域异位灰质的代谢活性及灌注情况可能代表了异常定位灰质的葡萄糖代谢及灌注，而非亚临床发作现象。因此，FGD-PET及HMPAO-SPECT被发现是磁共振成像评估PNH时的有用补充。