Honda O, Johkoh T, Ichikado K, Yoshida S, Mihara N, Higashi M, Tomiyama N, Maeda M, Hamada S, Naito H, Takeuchi N, Yamamoto S, Nakamura H
Department of Radiology, Osaka University Medical School, Suita, Japan.
J Comput Assist Tomogr. 1999 May-Jun;23(3):374-9. doi: 10.1097/00004728-199905000-00010.
The purpose of this study was to determine distinguishing features of three diseases that are distributed along the lymphatics.
CT scans of 40 patients with lymphangitic carcinomatosis, 41 with sarcoidosis, and 44 with malignant lymphoma were retrospectively reviewed. We evaluated the degree of involvement of the interlobular septa, bronchovascular structures, subpleural interstitium, and other CT findings.
The number of thickened interlobular septa and the extent of involvement of the subpleural interstitium in lymphangitic carcinomatosis were higher than those in sarcoidosis and malignant lymphoma (p<0.0001). Nodules of >1 cm in diameter were more often seen in malignant lymphoma (41.0%) than in the other two diseases (p < 0.001). Bilateral distribution was more common in sarcoidosis (100%) than in the others (p<0.001).
The major difference among lymphangitic carcinomatosis, sarcoidosis, and malignant lymphoma is the greater involvement of the interlobular septa and subpleural interstitium in lymphangitic carcinomatosis than in either sarcoidosis or malignant lymphoma.
本研究的目的是确定三种沿淋巴管分布的疾病的鉴别特征。
回顾性分析40例淋巴管癌病患者、41例结节病患者和44例恶性淋巴瘤患者的CT扫描结果。我们评估了小叶间隔、支气管血管结构、胸膜下间质的受累程度以及其他CT表现。
淋巴管癌病中小叶间隔增厚的数量和胸膜下间质的受累程度高于结节病和恶性淋巴瘤（p<0.0001）。直径>1 cm的结节在恶性淋巴瘤中（41.0%）比在其他两种疾病中更常见（p < 0.001）。双侧分布在结节病中（100%）比在其他疾病中更常见（p<0.001）。
淋巴管癌病、结节病和恶性淋巴瘤之间的主要差异在于，与结节病或恶性淋巴瘤相比，淋巴管癌病中小叶间隔和胸膜下间质的受累程度更大。
