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[Effect of aflatoxin B1 in vitro and in vivo].

作者信息

Shabad L M, Kolesnichenko T S, Nikonova T V

出版信息

Biull Eksp Biol Med. 1976;82(11):1349-52.

PMID:1035116
Abstract

The direct and transplacental action of aflatoxin B1 was studied on organic cultures of the embryonic pulmonary tissue of mice of the A line, BD-IX rats and golden hamsters (Cricetus auratus W.). Its toxic action on the cultures and the absence of any blastomogenic effect was demonstrated. In experiments on mice the transplacental penetration of aflatoxin B1 led to an increase in the incidence of the breast tumours in the progeny.

摘要

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