Kouraklis G, Misiakos E, Papachristodoulou A, Papavasiliou V, Glinavou A, Karatzas G
Faculty of Medicine, School of Health Science, University of Athens, Greece.
Acta Chir Belg. 1999 Apr;99(2):59-63.
A retrospective study on patients with gastric cancer during the periods 1984-88 (n = 63 patients) and 1989-93 (n = 59 patients) was made. The aim of the study was to assess any changing patterns in tumour distribution, surgical management and survival during the two periods. When the diagnosis was made, the majority of tumours were advanced: 58 were stage IV and 21 were stage IIIB, with 43 tumours at earlier stages. The incidence of proximally located gastric adenocarcinomas increased from 15.9 to 27.1%, while the incidence of carcinomas located in the body decreased from 34.9 to 23.7%. The majority of patients underwent conservative gastrectomy. The proportion of proximal gastrectomies increased from 3.2 to 15.3 per cent (p = 0.02), whereas the proportion of combined resection of adjacent organs decreased from 38.1 to 22.0 per cent (p = 0.04). Perioperative mortality rate decreased from 17.5 to 1.7 per cent (p = 0.003). Prognosis remained unchanged in the two periods; overall 5-year survival is calculated as 12 per cent.
对1984 - 1988年期间（n = 63例患者）和1989 - 1993年期间（n = 59例患者）的胃癌患者进行了一项回顾性研究。该研究的目的是评估这两个时期肿瘤分布、手术治疗和生存方面的任何变化模式。确诊时，大多数肿瘤已属晚期：58例为IV期，21例为IIIB期，43例肿瘤处于早期阶段。近端胃腺癌的发病率从15.9%上升至27.1%，而胃体部癌的发病率从34.9%降至23.7%。大多数患者接受了保守性胃切除术。近端胃切除术的比例从3.2%增至15.3%（p = 0.02），而相邻器官联合切除术的比例从38.1%降至22.0%（p = 0.04）。围手术期死亡率从17.5%降至1.7%（p = 0.003）。两个时期的预后保持不变；总体5年生存率计算为12%。
