Hameleers J A, Zeebregts C J, Hamerlijnck R P, Elbers J R, Hameeteman T M
Department of Cardiothoracic Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.
Acta Chir Belg. 1999 Apr;99(2):92-4.
Intravenous leiomyomatosis with cardiac extension is a rare entity. The case of a 49-year-old patient is described: she was operated on for intracaval intra-atrial leiomyomatosis. After an incomplete procedure (the tumour appeared not totally resectable), the patient was treated for a period of three years with a GnRH-analogue, whereafter the patient was doing clinically well and the tumour, although it regained some growth, was in a stable situation. This new strategy seems of certain importance to the surgeon, as it carries an alternative to a high-risk reoperation. To our knowledge, this is the first description of such a combined therapeutical approach.
伴有心脏受累的静脉内平滑肌瘤病是一种罕见疾病。本文描述了一位49岁患者的病例:她因腔静脉内心房平滑肌瘤病接受手术。在手术不完整(肿瘤似乎无法完全切除)后,患者接受了三年的促性腺激素释放激素类似物治疗,此后患者临床状况良好,肿瘤虽有一定程度的复发,但处于稳定状态。这种新策略对外科医生似乎具有一定重要性,因为它为高风险再次手术提供了一种替代方案。据我们所知,这是对这种联合治疗方法的首次描述。