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1980年至1995年美国印第安人和阿拉斯加原住民儿童中的川崎病

Kawasaki syndrome among American Indian and Alaska Native children, 1980 through 1995.

作者信息

Holman R C, Belay E D, Clarke M J, Kaufman S F, Schonberger L B

机构信息

Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA.

出版信息

Pediatr Infect Dis J. 1999 May;18(5):451-5. doi: 10.1097/00006454-199905000-00010.

DOI:10.1097/00006454-199905000-00010
PMID:10353519
Abstract

BACKGROUND

Kawasaki syndrome (KS) is a leading cause of acquired heart disease among US children, but the epidemiologic features of KS among American Indian and Alaska Native (AI/AN) children have not been described.

METHODS

We examined Indian Health Service computerized records of hospital discharges for AI/AN children <18 years of age with KS during 1980 through 1995.

RESULTS

During 1980 through 1995, 85 AI/AN children were reported with a hospitalization for KS; 10 of the children had an additional KS hospitalization record within 5 months. The average annual KS hospitalization rate for children <5 years of age, based on first KS hospitalization only, was 4.3 cases per 100000 children; the rate for children age <1 year (n = 21) was 8.6 per 100000 and for children ages 1 to 4 years was 3.6 per 100000. The annual rates for children < 5 years of age ranged from 0 to 8.5 per 100000 children. KS hospitalizations for children peaked in January and February; 50.6% of the children were hospitalized during January through April. The overall median length of hospital stay was 4 days (range, 1 to 29 days); the median duration decreased from 8 days from 1980 through 1982 to 4 days from 1993 through 1995.

CONCLUSIONS

The overall annual hospitalization rate of KS among AI/AN children <5 years of age was slightly lower than rates for several majority white populations in the United States. (4.6 to 15.2 cases per 100000) and much lower than rates for blacks and Asians/Pacific Islanders.

摘要

背景

川崎病(KS)是美国儿童后天性心脏病的主要病因,但美国印第安人和阿拉斯加原住民(AI/AN)儿童川崎病的流行病学特征尚未得到描述。

方法

我们查阅了印第安卫生服务局1980年至1995年期间18岁以下患有川崎病的AI/AN儿童的医院出院计算机记录。

结果

1980年至1995年期间,报告有85名AI/AN儿童因川崎病住院治疗;其中10名儿童在5个月内有额外的川崎病住院记录。仅基于首次川崎病住院情况,5岁以下儿童的川崎病年住院率为每10万名儿童4.3例;1岁以下儿童(n = 21)的年住院率为每10万名儿童8.6例,1至4岁儿童的年住院率为每10万名儿童3.6例。5岁以下儿童的年住院率在每10万名儿童0至8.5例之间。儿童川崎病住院人数在1月和2月达到峰值;50.6%的儿童在1月至4月住院。住院总中位时长为4天(范围为1至29天);中位时长从1980年至1982年的8天降至1993年至1995年的4天。

结论

5岁以下AI/AN儿童川崎病的总体年住院率略低于美国几个多数白人人群的年住院率(每10万人中有4.6至15.2例),且远低于黑人和亚裔/太平洋岛民的年住院率。

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