Chin P T, Gallagher P J, Stephen M S
Department of Upper Gastrointestinal Surgery and Total Parenteral Nutrition, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
Aust N Z J Surg. 1999 May;69(5):391-2. doi: 10.1046/j.1440-1622.1999.01579.x.
In the course of oncological surgery, resection of the inferior vena cava (IVC) may be required to obtain an adequate resection margin and to offer the best opportunity of cure. The remaining defect in the IVC may be managed by: (i) primary repair which may lead to subsequent narrowing of the lumen, possibly leading to turbulent flow and thrombus formation; (ii) patch grafting of the defect, which may prevent narrowing. Several synthetic and biosynthetic materials are available as patch grafts and autologous pericardium has also been used.
The harvesting and use of the autogenous peritoneo-fascial (APF) graft as an alternative caval patch graft material in the management of defects in the caval wall is proposed. Autogenous peritoneo-fascial caval patch graft repair in six patients was undertaken.
One patient with leiomyosarcoma secondaries in the liver eventually succumbed to the disease. The other five patients are clinically well with no evidence of IVC obstruction or venous aneurysms.
Preliminary results show that this new technique of utilizing an APF patch graft for caval repair is clinically a suitable alternative to current biosynthetic and synthetic materials and may in fact be superior in many aspects.
在肿瘤外科手术过程中,可能需要切除下腔静脉(IVC)以获得足够的切除边缘并提供最佳的治愈机会。下腔静脉的剩余缺损可通过以下方法处理:(i)一期修复,这可能导致随后的管腔狭窄,可能导致血流紊乱和血栓形成;(ii)缺损补片移植,这可能防止狭窄。有几种合成材料和生物合成材料可作为补片移植材料,自体心包也已被使用。
提出采用自体腹膜 - 筋膜(APF)移植物作为替代腔静脉补片移植材料来处理腔静脉壁缺损。对6例患者进行了自体腹膜 - 筋膜腔静脉补片移植修复。
1例肝脏平滑肌肉瘤转移患者最终死于该疾病。其他5例患者临床状况良好,没有下腔静脉阻塞或静脉瘤的证据。
初步结果表明,这种利用APF补片移植进行腔静脉修复的新技术在临床上是目前生物合成材料和合成材料的合适替代方法,并且实际上可能在许多方面更具优势。