Wallis R C, Hayes C G
Yale J Biol Med. 1976 Nov;49(5):439-45.
The problem of evaluating the epidemic potential of western equine encephalitis in the northeastern United States is presented and possible reasons are discussed for the present lack of human and horse cases of this disease even though increased numbers of isolations of the virus have been obtained in the East during recent years. Epidemiologic factors of vector bionomics and virus strain variations are considered. It is concluded that while this virus strain can no longer be regarded as uncommon in the Northeast, the evidence indicates there is little potential for epidemic expression of this agent in the human and horse population. This appears to be due to differences in the bionomics of the mosquito Culiseta melanura, which serves as the primary enzootic vector in the northeastern United States and in the bionomics of Culex tarsalis that is the vector in the western region of the United States. Other limiting factors in the epidemic potential may be variations between virus strains located in the East and West.
本文提出了评估美国东北部西部马脑炎流行潜力的问题,并讨论了尽管近年来在东部地区分离出该病毒的数量有所增加,但目前缺乏该疾病人类和马匹病例的可能原因。文中考虑了媒介生物学特性和病毒株变异等流行病学因素。得出的结论是,虽然这种病毒株在东北部已不再被视为罕见,但证据表明,该病原体在人类和马匹群体中几乎没有流行的潜力。这似乎是由于在美国东北部作为主要动物疫源地媒介的黑尾库蚊的生物学特性,与在美国西部地区作为媒介的致倦库蚊的生物学特性存在差异。流行潜力的其他限制因素可能是东部和西部病毒株之间的变异。