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Medpor动力耦合柱:一种兔模型。

Medpor Motility Coupling Post: a rabbit model.

作者信息

Choi J C, Iwamoto M A, Bstandig S, Rubin P A, Shore J W

机构信息

Limberg Eye Surgery, San Luis Obispo, California, USA.

出版信息

Ophthalmic Plast Reconstr Surg. 1999 May;15(3):190-201. doi: 10.1097/00002341-199905000-00009.

Abstract

PURPOSE

To verify if a Medpor porous polyethylene orbital implant (PPOI) (Porex Surgical, Atlanta, GA, U.S.A.), once vascularized, will tolerate a partially exposed titanium screw on its anterior surface.

METHODS

Ten New Zealand white rabbits were enucleated and given Medpor PPOIs. Eight weeks postoperatively, Medpor Motility Coupling Posts (MCPs) (Porex Surgical) were placed into the orbital implants. Clinical tissue tolerance and histologic response to the new device were noted.

RESULTS

The titanium screws were well tolerated by the animals. No case of post-operative infection, conjunctival inflammation, conjunctival erosion, MCP dislocation, or PPOI fragmentation was noted. A fibrous tissue growth over the titanium head was noted in all screws with a head height of 2.5 mm. The fibrous tissue overgrowth was not observed in screws with a head height of 4 mm or more.

CONCLUSION

During the 6-month observation period, all implanted Medpor MCPs demonstrated favorable tissue tolerance and stable interfaces between the MCP and the conjunctiva and between the MCP and the PPOI.

摘要

目的

验证一种Medpor多孔聚乙烯眼眶植入物(PPOI)(美国佐治亚州亚特兰大市Porex Surgical公司生产)一旦血管化后,其前表面部分暴露的钛螺钉是否能被耐受。

方法

对10只新西兰白兔进行眼球摘除并植入Medpor PPOI。术后8周,将Medpor活动耦合柱(MCP)(Porex Surgical公司生产)植入眼眶植入物中。记录临床组织耐受性以及对新装置的组织学反应。

结果

动物对钛螺钉耐受性良好。未发现术后感染、结膜炎症、结膜糜烂、MCP脱位或PPOI碎裂的情况。在所有头部高度为2.5毫米的螺钉上,均观察到钛钉头部有纤维组织生长。在头部高度为4毫米或更高的螺钉上未观察到纤维组织过度生长。

结论

在6个月的观察期内,所有植入的Medpor MCP均表现出良好的组织耐受性,且MCP与结膜之间以及MCP与PPOI之间的界面稳定。

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