Yoshikawa M, Terada Y, Toda T
Department of Endodontics, Osaka Dental University, Japan.
J Osaka Dent Univ. 1998 Oct;32(2):67-70.
We developed a new type of calcium phosphate cement for clinical use in endodontics as a root canal sealer or pulp cupping agent. The solid phase of the sealer is composed of 70% of alpha-tricalcium phosphate (alpha-TCP) and 30% of titanic oxide (TiO2), and the liquid phase is 37% citric acid, 5% tannic acid and 58% distilled water. TiO2 was added to control setting time and handling of the cement. We used commercially available calcium phosphate root canal sealer as a control. ISO standards specify that new endodontic products should be examined thoroughly before clinical use. It is important to carry out in vitro cytotoxicity and in vivo histocompatibility tests. We first did in vitro test of setting time and root canal sealing ability of the cement. We found that this developed calcium phosphate cement had an appropriate setting time and excellent sealing ability as a root canal sealer, and concluded that it was suitable for clinical use as a root canal sealer.
我们研发了一种新型磷酸钙骨水泥，用于牙髓病学临床，作为根管封闭剂或牙髓盖髓剂。该封闭剂的固相由70%的α-磷酸三钙（α-TCP）和30%的二氧化钛（TiO₂）组成，液相为37%的柠檬酸、5%的单宁酸和58%的蒸馏水。添加TiO₂以控制骨水泥的凝固时间和操作性。我们使用市售的磷酸钙根管封闭剂作为对照。ISO标准规定，新型牙髓病产品在临床使用前应进行全面检查。进行体外细胞毒性和体内组织相容性测试很重要。我们首先对骨水泥的凝固时间和根管封闭能力进行了体外测试。我们发现，这种研发的磷酸钙骨水泥作为根管封闭剂具有合适的凝固时间和出色的封闭能力，并得出结论，它适合作为根管封闭剂用于临床。
