Velebit V, al-Tawil D
Klinika za kardiohirurgiju, Klinicki centar Sarajevo.
Med Arh. 1999;53(1):33-6.
The paper is a case report of a 34 year old man with an inferior wall myocardial infarction, episodes of ventricular tachycardia, normal coronary arteries and a large atrial septal defect. Coronary atherosclerosis causes 95% of all myocardial infarcts and 75% in the age group under 35 years. Other possible causes are coronary arteritis, trauma, valuvlopathy, systemic diseases, infective and non-infective endocarditis, polycithemia, thrombocytosis, cocaine abuse. These can be usually excluded by history, physical or laboratory examination. The existence of a large atrial septal defect with dominantly left to right shunting, but occasional right to left shunting, is an indication and a justification for surgical treatment aiming to prevent recurrence by closure of the atrial septal defect. Paradoxical emboli have been recognised in the recent literature as an important cause of cerebral infarction, more rarely of emboli to other locations. The etiology remains difficult to confirm with certitude except when an embolus is seen by echocardiography in transit through a patent foramen ovale. We have also reviewed previously published cases of paradoxical emboli in literature.
本文是一例34岁男性患者的病例报告,该患者患有下壁心肌梗死、室性心动过速发作、冠状动脉正常且存在大型房间隔缺损。冠状动脉粥样硬化导致了95%的心肌梗死,在35岁以下年龄组中占75%。其他可能的病因包括冠状动脉炎、创伤、瓣膜病、全身性疾病、感染性和非感染性心内膜炎、红细胞增多症、血小板增多症、可卡因滥用。这些通常可通过病史、体格检查或实验室检查排除。存在大型房间隔缺损且以左向右分流为主,但偶尔有右向左分流,这是通过闭合房间隔缺损来预防复发的手术治疗的指征和依据。反常栓塞在最近的文献中已被确认为脑梗死的重要原因,较少是其他部位栓塞的原因。除了通过超声心动图看到栓子通过卵圆孔未闭移动外,病因仍难以确切证实。我们还回顾了文献中先前发表的反常栓塞病例。