Ota Y, Karakida K, Watanabe D, Miyasaka M, Tsukinoki K
Department of Oral Surgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Tokai J Exp Clin Med. 1998 Oct;23(4):157-65.
A case of central carcinoma of the mandible arising from a recurrent odontogenic keratocyst is reported. A 38-year-old man was admitted to the Tokai University Hospital due to postoperative infection of a recurrent odontogenic keratocyst of the left mandible. He had had a cystectomy for an odontogenic keratocyst 4 years ago. The lesion revealed bony destruction of the mandible with worm-eating shaped margins with extension to the facial skin. A biopsy specimen revealed squamous cell carcinoma. The mandible was resected with facial skin and the sublingual space was dissected to preserve the lingual nerve. The oral and the facial resections were reconstructed with a titanium plate and bilateral rectus abdominis myocutaneous free flaps. The plate was removed due to infection around the margins and readjustment of the flaps was conducted 5 months after the surgery. He has not had a local relapse, metastasis, or incisional hernia for 8 months following surgery. Good occlusion has been attained by the residual mandible, and he is able to eat without any problems.
报告1例起源于复发性牙源性角化囊肿的下颌骨中央癌。一名38岁男性因左下颌骨复发性牙源性角化囊肿术后感染入住东海大学医院。他4年前曾因牙源性角化囊肿接受过囊肿切除术。病变显示下颌骨骨质破坏,边缘呈虫蚀状,并延伸至面部皮肤。活检标本显示为鳞状细胞癌。切除下颌骨及面部皮肤,并解剖舌下间隙以保留舌神经。用钛板和双侧腹直肌肌皮游离皮瓣重建口腔和面部切除部位。术后5个月,因边缘感染取出钛板并对皮瓣进行了调整。术后8个月,他未出现局部复发、转移或切口疝。残余下颌骨实现了良好的咬合,他能够正常进食。