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植物状态的临床病理研究——植物状态与脑死亡的鉴别

[Clinicopathological studies of the vegetative state--distinction between the vegetative state and brain death].

作者信息

Ogashiwa M, Takeuchi K

出版信息

No To Shinkei. 1976 Sep;28(9):901-12.

PMID:1036078
Abstract

10 cases showing vegetative state and 2 cases of brain death due to severe brain damage were observed and the differences of clinicopathological findings between both states were discussed. The cases of vegetative state can be divided into three groups, first is widespread lesion in the cerebral cortex, second is in the cerebral white matter and third is in the brain stem. While, the diffuse whole brain damage including the vegetative center of the central nervous system causes brain death. We should like to emphasize that the most important structure to maintain the human life is the vital center in the brain stem, and that a human being, in whom only those function can be preserved, is possible to be alive as vegetative state. Prognostic value of the EEG indicating quality of survival noted in early stage after severe brain damage has not so important as the flat EEG revealed in brain death.

摘要

观察了10例植物状态患者和2例因严重脑损伤导致脑死亡的患者,并讨论了两种状态下临床病理表现的差异。植物状态的病例可分为三组,第一组是大脑皮层广泛病变,第二组是脑白质病变,第三组是脑干病变。而包括中枢神经系统植物神经中枢在内的弥漫性全脑损伤会导致脑死亡。我们想强调的是,维持人类生命最重要的结构是脑干中的生命中枢,只有那些功能得以保留的人有可能以植物状态存活。严重脑损伤后早期脑电图对生存质量的预后价值不如脑死亡时出现的脑电图平坦重要。

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