[Change in the estrous cycle of mice under the effect of prostaglandin F2 alpha].

It was shown that specific reception in female mice to prostaglandine F2alpha maturated in the process of ontogenesis since the vaginal reaction and the weight of the reproductive organs in the immature female animals failed to alter under its effect. In the sexually mature mice prostaglandine F2alpha arrested the course of the estral cycle and caused an untimely occurrence of the next estrus for a more prolonged time than normal, irrespective of the phase of the estral cycle during which it was administered.