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[新生儿消化性溃疡发病机制的动物实验研究]

[Animal-experiment studies on the pathogenesis of peptic ulcer in the newborn].

作者信息

Brückner W L, Kernert B, Loeweneck H, Schmahl W, Holle F, Fonkalsrud E W

出版信息

Langenbecks Arch Chir. 1976;Suppl:233-7.

PMID:1036412
Abstract

Gastric secretion was studied in 188 fetuses of 28 pregnant dogs near term. Baseline secretory values were determined and gastric secretion was stimulated in additional fetuses with histamine, insulin, or gastrin. A significant increase in volume, acidity and pepsin output was observed in fetuses stimulated during the last week of gestation. Following maternal stimulation the placental transfer of histamine, insulin, and gastrin are demonstrated.

摘要

对28只近足月妊娠母犬的188只胎儿的胃分泌情况进行了研究。测定了基础分泌值,并使用组胺、胰岛素或胃泌素对其他胎儿的胃分泌进行刺激。在妊娠最后一周受到刺激的胎儿中,观察到胃液量、酸度和胃蛋白酶分泌量显著增加。在母体受到刺激后,证实了组胺、胰岛素和胃泌素可通过胎盘转运。

相似文献

1
[Animal-experiment studies on the pathogenesis of peptic ulcer in the newborn].[新生儿消化性溃疡发病机制的动物实验研究]
Langenbecks Arch Chir. 1976;Suppl:233-7.
2
Gastric secretion in the canine fetus following maternal stimulation: experimental studies on placental transfer of insulin, histamine, and gastrin.母体刺激后犬胎儿的胃分泌:胰岛素、组胺和胃泌素胎盘转运的实验研究
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