早期胚胎发育过程中合成的心肌糖肽的组织特异性。

Tissue specificity of myocardial glycopeptides synthesized during early embryonic development.

作者信息

Manasek F J, Lacktis J W

出版信息

Recent Adv Stud Cardiac Struct Metab. 1976;12:13-7.

Abstract

[3H] Glucosamine-labeled glycopeptides synthesized by hearts from stage 14-16 chick embryos were separated on DE-52 by ion-exchange chromatography and compared to those synthesized in other parts of the embryo at the same stage. Relatively few molecular species were present in all tissues, and they appeared closely homologous. There were no glycopeptides unique to any embryonic region examined, suggesting that tissue specificity may result from quantitative rather than qualitative differences in glycopeptides.

摘要

用[3H]葡糖胺标记14至16期鸡胚心脏合成的糖肽，通过离子交换色谱在DE - 52上进行分离，并与同一阶段胚胎其他部位合成的糖肽进行比较。所有组织中存在的分子种类相对较少，且它们似乎具有密切的同源性。在所检测的任何胚胎区域均不存在独特的糖肽，这表明组织特异性可能是由糖肽的数量差异而非质量差异导致的。