Sambola A, Sanz G
Institut de Malalties Cardiovasculares, Hospital Clínic, IDIBAPS, Universitat de Barcelona.
Rev Esp Cardiol. 1999;52 Suppl 1:55-60.
At present it is generally accepted that unstable angina and non-Q-wave myocardial infarction have a common underlying pathophysiology, however, clinical presentation and outcome of these syndromes depend on the location, grade and duration of myocardial ischemia. The most important difference between both syndromes is the myocardial necrosis from non-Q myocardial infarction, which may carry a higher risk death and reinfarction rate and for that reason a worse prognosis than unstable angina. Some studies suggest that the effect of antithrombotic treatment can be different in both syndromes. Nevertheless the differences do not achieve significance in most of these studies.
目前，人们普遍认为不稳定型心绞痛和非Q波心肌梗死具有共同的潜在病理生理学机制，然而，这些综合征的临床表现和预后取决于心肌缺血的部位、程度和持续时间。这两种综合征最重要的区别在于非Q波心肌梗死会出现心肌坏死，这可能导致更高的死亡风险和再梗死率，因此预后比不稳定型心绞痛更差。一些研究表明，抗血栓治疗在这两种综合征中的效果可能不同。然而，在大多数这些研究中，差异并不显著。
