Int J Gynaecol Obstet. 1999 Mar;64(3):323-33.
The incidence of twins, triplets, and higher-order multiple gestations has increased dramatically because of widespread use of ovulation-inducing drugs and advanced assisted reproductive techniques. There is considerable perinatal/maternal morbidity and mortality associated with multifetal gestations. The practicing obstetrician managing these high-risk patients should be familiar with their special antepartum and intrapartum problems. The obstetrician-gynecologist unaccustomed to caring for patients with a multifetal gestation should consult with maternal-fetal medicine specialists who have expertise in managing these pregnancies. Better use of infertility modalities, early diagnosis of the multiple pregnancy, prevention of preterm birth, close fetal surveillance, and atraumatic labor and delivery can improve perinatal outcome in the multifetal gestation.
由于促排卵药物的广泛使用和先进的辅助生殖技术,双胞胎、三胞胎及更高阶多胎妊娠的发生率急剧上升。多胎妊娠伴有相当多的围产期/孕产妇发病率和死亡率。管理这些高危患者的执业产科医生应熟悉其特殊的产前和产时问题。不习惯于照顾多胎妊娠患者的妇产科医生应咨询在管理这些妊娠方面具有专业知识的母胎医学专家。更好地利用不孕治疗方法、早期诊断多胎妊娠、预防早产、密切监测胎儿以及进行无创分娩,可以改善多胎妊娠的围产期结局。