Goovaerts H G, Faes T J, Raaijmakers E, Heethaar R M
Department of Medical Clinical and Informatics, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.
Med Biol Eng Comput. 1998 Sep;36(5):598-603. doi: 10.1007/BF02524430.
At relatively high frequencies, the application of an alternating current through the body or a body segment results in electromagnetic stray fields which reduce the amount of current actually injected into the tissue under study. This radiation effect can be reduced by use of a symmetrical configuration current source. The symmetry of such an arrangement, however, depends on the stray capacitances of the source with respect to surrounding equipment. To minimise these effects, it is required that the source is electrically isolated from the surrounding equipment and the subject under study. In this manner stray capacitances with respect to elements of the current source are reduced. In such a configuration common mode voltages to the input amplifier of the measuring system are also reduced. The paper describes design considerations and the implementation of a wideband current source capable of injecting alternating current in the order of 300 microARMS into biological tissue having impedances up to 1 k omega. Current stabilisation is obtained by means of a control circuit which measures the actual current passing through the tissue under study. Leakage currents arising from shielding and stray capacitances are compensated for. The usable frequency range is between 4 kHz and 1024 kHz and current stability is better than 0.2%. Through the use of a symmetrical, floating circuit a configuration is obtained which substantially reduces stray effects. The current source is connected to other circuits by means of two isolation ports: (1) a transformer coupling for the carrier frequency; and (2) an opto-coupler to transfer a phase reference signal obtained from current measurement. The current amplitude can be modulated by controlling the reference input to the control loop by means of a third auxiliary isolation port for transfer of the modulating signal.
在相对较高的频率下,通过身体或身体部位施加交流电会产生电磁杂散场,这会减少实际注入到所研究组织中的电流量。通过使用对称配置电流源可以降低这种辐射效应。然而,这种布置的对称性取决于源相对于周围设备的杂散电容。为了最小化这些影响,要求源与周围设备以及所研究的对象进行电气隔离。通过这种方式,相对于电流源元件的杂散电容得以减小。在这种配置中,测量系统输入放大器的共模电压也会降低。本文描述了一种宽带电流源的设计考虑因素及实现方式,该电流源能够向阻抗高达1 kΩ的生物组织中注入约300 μA有效值的交流电。通过一个控制电路实现电流稳定,该控制电路测量通过所研究组织的实际电流。对屏蔽和杂散电容产生的漏电流进行补偿。可用频率范围为4 kHz至1024 kHz,电流稳定性优于0.2%。通过使用对称的浮动电路,可获得一种能大幅降低杂散效应的配置。电流源通过两个隔离端口连接到其他电路:(1) 用于载波频率的变压器耦合;(2) 用于传输从电流测量中获得的相位参考信号的光耦合器。电流幅度可以通过利用第三个辅助隔离端口控制控制环路的参考输入来调制,该辅助隔离端口用于传输调制信号。