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表现为髓内肿块的脊髓结节病:一例报告

Spinal cord sarcoidosis presenting as an intramedullary mass: a case report.

作者信息

Wang P Y

机构信息

Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1999 Apr;62(4):250-4.

Abstract

A case of spinal cord sarcoidosis mimicking an intramedullary tumor is reported because of its rarity and difficulty in diagnosis before surgery. A 66-year-old woman began to suffer from chronic thoracic myelopathy in August, 1996. She had a history of intrathoracic sarcoidosis with left hilar adenopathy in 1991, which disappeared completely after steroid therapy for one month. Magnetic resonance imaging of the T-spine performed on 4 June, 1997, showed normal appearance in T1-weighted and T2-weighted images but abnormal enhancement at the T10-11 level. Open biopsy revealed noncaseating granulomatous inflammation and perivascular lymphocytic infiltration. Following biopsy, methylprednisolone 750 mg was given daily for three days followed by prednisolone 60 mg per day. The patient was discharged on 10 July, 1997, in a stable condition. She died on 22 July, 1997, at a local hospital due to urinary tract infection with sepsis.

摘要

报告一例脊髓结节病,因其罕见且术前诊断困难,易被误诊为髓内肿瘤。一名66岁女性于1996年8月开始出现慢性胸段脊髓病。她曾在1991年患胸内结节病伴左肺门淋巴结肿大,经一个月的类固醇治疗后完全消失。1997年6月4日进行的胸椎磁共振成像显示,T1加权和T2加权图像外观正常,但T10 - 11水平有异常强化。开放活检显示非干酪样肉芽肿性炎症和血管周围淋巴细胞浸润。活检后,每日给予甲基泼尼松龙750 mg,共三天,随后每日给予泼尼松龙60 mg。患者于1997年7月10日病情稳定出院。她于1997年7月22日在当地医院因尿路感染伴败血症死亡。

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