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一只金披风狐蝠(短吻果蝠)中与失蛋白性肾病相关的脑水肿。

Cranial edema associated with a protein-losing nephropathy in a golden-mantled flying fox (Pteropus pumilus).

作者信息

Deem S L, Heard D J, Clippinger T L, Buergelt C D

机构信息

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0126, USA.

出版信息

J Zoo Wildl Med. 1999 Mar;30(1):126-31.

PMID:10367654
Abstract

An adult golden-mantled flying fox (Pteropus pumilus) was diagnosed with nephrotic syndrome on the basis of the findings of proteinuria, hypoalbuminemia, hypercholesterolemia, and cranial edema. Membranoproliferative glomerulitis and interstitial nephritis were confirmed antemortem by renal biopsy. The bat had received seven injections of oxytocin in the period immediately prior to presentation. The possible role of oxytocin in the development of the nephropathy is discussed. Supportive care and treatment with a single plasma transfusion, furosemide, and prednisone led to a gradual but complete resolution of the nephrotic syndrome in this animal.

摘要

一只成年金披风狐蝠(短吻果蝠)根据蛋白尿、低白蛋白血症、高胆固醇血症和脑水肿的检查结果被诊断为肾病综合征。生前通过肾活检确诊为膜增生性肾小球肾炎和间质性肾炎。这只蝙蝠在出现症状前立即接受了七次催产素注射。文中讨论了催产素在肾病发展中可能起到的作用。支持性护理以及单次输血、呋塞米和泼尼松治疗使该动物的肾病综合征逐渐完全缓解。

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