Belka C, Ottinger H, Kreuzfelder E, Weinmann M, Lindemann M, Lepple-Wienhues A, Budach W, Grosse-Wilde H, Bamberg M
Department of Radiation Oncology, Eberhard Karls University Tübingen, Germany.
Radiother Oncol. 1999 Feb;50(2):199-204. doi: 10.1016/s0167-8140(98)00130-3.
Immune cells subsets were prospectively analyzed after localized radiotherapy (LRT). LRT reduced the levels of all lymphocyte subsets, with B-cells and naive T-cells being most sensitive. Lymphocyte function was suppressed, but still within the normal range. Rapid recovery of cytotoxic T-cells/natural killer cells after LRT and the functional suppression within normal levels explains the low incidence of infections after LRT.
在局部放疗（LRT）后对免疫细胞亚群进行前瞻性分析。LRT降低了所有淋巴细胞亚群的水平，其中B细胞和初始T细胞最为敏感。淋巴细胞功能受到抑制，但仍在正常范围内。LRT后细胞毒性T细胞/自然杀伤细胞的快速恢复以及功能抑制在正常水平内解释了LRT后感染发生率较低的原因。
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