Miller M R, Thompson W R, Casella J F, Spevak P J
Division of Pediatric Cardiology, Johns Hopkins University, 600 North Wolfe Street, Baltimore, MD 21287, USA.
Pediatr Cardiol. 1999 Jul-Aug;20(4):287-9. doi: 10.1007/s002469900465.
Spontaneous echocardiographic contrast is well reported in states of low flow and low shear stress, and the primary blood component involved has been reported as red blood cells via rouleaux formation. This report describes the occurrence of spontaneous echocardiographic contrast from a unique mechanism of IgM-mediated red blood cell agglutination and describes the clinical sequelae.
