Davison H C, French N P, Trees A J
Department of Veterinary Clinical Science and Animal Husbandry, Faculty of Veterinary Science, University of Liverpool Veterinary Teaching Hospital, Leahurst, Neston, South Wirral.
Vet Rec. 1999 May 15;144(20):547-50. doi: 10.1136/vr.144.20.547.
All the cattle in 14 dairy herds in England were tested for Neospora caninum-specific antibodies with a commercial ELISA. Three of the herds had had sporadic abortions, eight had had endemic abortions and three had had epidemic abortions associated with N caninum before the study. Of 4295 cattle tested, 17.1 per cent were seropositive and the herd-specific prevalence ranged from 7.3 per cent to 44.8 per cent. No significant effect of either herd size (P = 0.988), endemic (P = 0.869) or epidemic (P = 0.138) patterns of abortion on herd-specific prevalence was found by using logistic regression analysis. There was no evidence in any herd of a significant increase in prevalence with age; the prevalence in seven-to 12-month-old cattle was not significantly different (P > 0.400) from the prevalence in older cattle, except that there was a significantly lower prevalence (P = 0.017) in 13-to 24-month-old cattle. The results of this study are consistent with vertical transmission being the major route of N caninum transmission in these herds.
采用商用酶联免疫吸附测定法（ELISA）对英格兰14个奶牛场的所有奶牛进行了犬新孢子虫特异性抗体检测。在研究之前，其中3个牛群曾发生过散发性流产，8个牛群曾发生过地方性流产，3个牛群曾发生过与犬新孢子虫有关的流行性流产。在检测的4295头奶牛中，17.1%呈血清阳性，牛群特异性患病率在7.3%至44.8%之间。通过逻辑回归分析发现，牛群规模（P = 0.988）、地方性（P = 0.869）或流行性（P = 0.138）流产模式对牛群特异性患病率均无显著影响。在任何牛群中均未发现患病率随年龄显著增加的证据；7至12月龄奶牛的患病率与年龄较大奶牛的患病率无显著差异（P > 0.400），不过13至24月龄奶牛的患病率显著较低（P = 0.017）。本研究结果与垂直传播是这些牛群中犬新孢子虫传播的主要途径这一观点相符。
