某些人类重症联合免疫缺陷（SCID）重建细胞上不存在CD34。
Absence of CD34 on some human SCID-repopulating cells.
作者信息
Dick J E
机构信息
Program in Cancer, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
出版信息
Ann N Y Acad Sci. 1999 Apr 30;872:211-7; discussion 217-9. doi: 10.1111/j.1749-6632.1999.tb08466.x.
Abstract
The availability of in vivo repopulation assays has greatly aided the study of human hematopoietic stem cells. Here, I shall review recent data that has identified a novel class of human repopulating cells that do not express classical stem cell markers including CD34 but still retain the ability to repopulate nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice.
摘要
体内再增殖试验的可用性极大地促进了对人类造血干细胞的研究。在此，我将回顾最近的数据，这些数据鉴定出了一类新型的人类再增殖细胞，它们不表达包括CD34在内的经典干细胞标志物，但仍保留再增殖非肥胖糖尿病/重症联合免疫缺陷（NOD/SCID）小鼠的能力。
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