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[90岁高龄患者的动脉心肌血运重建。个人经验及文献综述]

[Arterial myocardial revascularization in the 9th decade of life. Personal results and review of the literature].

作者信息

Mortasawi A, Ennker I C, Albert A, Rosendahl U, Dalladaku F, Alexander T, Ennker J

机构信息

Klinik für Herz-, Thorax- und Gefässchirurgie, Herzzentrum Lahr/Baden.

出版信息

Herz. 1999 Apr;24(2):158-70. doi: 10.1007/BF03043855.

Abstract

The rate of the population being 80 years of age and even older, has an increasing tendency in the Federal Republic of Germany. In 1996, a total of 87,372 patients received surgery supported by the heart-lung-machine, 2,383 patients out of these (2.7%) were 80 years of age and older. In view of the limited life expectance, the arterial revascularization in this age category is faced with controverse discussions. We analysed our patients in relation to this aspect. Between January 1, 1995 and June 30, 1997, 4,338 patients underwent surgery supported by the heart-lung-machine. Hundred and fifty-five out of these (3.6%) were in the 9th decade of life. Seventy-seven patients out of the 155 (49.7%, 34 women, 43 men, 80 to 88 years old, mean: 82 years of age) underwent an isolated myocardial revascularization. We performed 55 (71%) elective, 16 (21%) urgent and 6 (8%) emergency surgeries. Twelve patients (15.6%) solely received venous bypasses (Group I), 65 (84.4%) additionally also received unilateral bypasses of the internal mammaria artery (IMA) (Group II). Three patients died at our facility (3.9%), 3 further patients died during the follow-up treatment in outlying hospitals, the in-patient mortality rate in Group I therefore presented a rate of 8.3%, in Group II 7.7% and in total, a rate of 7.8%. In 1996, the in-patient mortality rate could be reduced to 3.6%. The follow-up observation time ranged between 7 and 138 weeks (median 44 weeks). The survival rate for patients with an IMA-bypass after 1 year was 86.3%, after 2 years 77%, and for the entire collective 85.3% and 75%. Whereas 96% of the patients could pre-operatively be related to Class III or IV of the NYHA-classification, 55 of the 63 survivors (87%) belonged to Class I (6%) or II (81%). Two Group I patients (22.2%), 3 Group II patients (5.6%) and 7.9% of the total collective complained about repeated angina symptoms. The myocardial revascularization with the internal mammaria artery performed on patients in the 9th decade of life, achieves an acceptable morbidity and mortality compared to solely venous coronary bypasses. The more prolonged follow-up observation period will clarify, whether the arterial myocardial revascularization also proves to be the superior method in this age category.

摘要

在德意志联邦共和国,80岁及以上人口的比例呈上升趋势。1996年,共有87372名患者接受了心肺机支持下的手术,其中2383名患者(2.7%)为80岁及以上。鉴于预期寿命有限,这一年龄段的动脉血运重建面临着争议性的讨论。我们从这方面对我们的患者进行了分析。在1995年1月1日至1997年6月30日期间,4338名患者接受了心肺机支持下的手术。其中155名(3.6%)患者处于90岁年龄段。155名患者中有77名(49.7%,34名女性,43名男性,年龄在80至88岁之间,平均年龄82岁)接受了单纯心肌血运重建。我们进行了55例(71%)择期手术、16例(21%)急诊手术和6例(8%)紧急手术。12名患者(15.6%)仅接受了静脉搭桥手术(第一组),65名患者(84.4%)还额外接受了单侧乳内动脉(IMA)搭桥手术(第二组)。3名患者在我们医院死亡(3.9%),另有3名患者在外地医院的后续治疗中死亡,因此第一组的住院死亡率为8.3%,第二组为7.7%,总体死亡率为7.8%。1996年,住院死亡率可降至3.6%。随访观察时间为7至138周(中位数44周)。接受IMA搭桥手术的患者1年后生存率为86.3%,2年后为77%,而整个群体的1年和2年生存率分别为85.3%和75%。术前96%的患者可归为纽约心脏协会(NYHA)分级的III级或IV级,63名幸存者中有55名(87%)属于I级(6%)或II级(81%)。第一组有2名患者(22.2%)、第二组有3名患者(5.6%)以及整个群体的7.9%抱怨有反复心绞痛症状。与单纯静脉冠状动脉搭桥手术相比,对90岁年龄段患者进行乳内动脉心肌血运重建的发病率和死亡率是可以接受的。更长时间的随访观察期将阐明,在这一年龄段动脉心肌血运重建是否也被证明是更优的方法。

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