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[持续颅内压、脑灌注压监测与重型颅脑损伤预后的关系]

[Relation of continuous ICP, CPP monitoring with prognosis for severe brain injury].

作者信息

Zhang W, Zhang X, Yi S

机构信息

Department of Neurosurgery, Air Force Hospital, Urumqi.

出版信息

Zhonghua Wai Ke Za Zhi. 1997 Feb;35(2):114-6.

PMID:10374491
Abstract

We analysed the treatment results of two groups of patients. Group I included 50 patients with severe brain injury with GCS 3-8, on whom continuous intracranial pressure (ICP) and cerebral perfusion pressure (CPP) monitoring was performed and Group II included 50 cases of similar patients, on whom no continuous ICP monitoring was performed. In Group I 8 patients had normal ICP (< 2.0 kPa), CPP (> 9.33 kpa), and the rest 42 had increased, ICP and reduced CPP. After adequate intervention including operation and drug treatment, group I patients had good results with a mortality of 14%. Group II patients received the same intervention based on clinical observations, but they had relatively worse results. We are of the opinion that continuous ICP and CPP monitoring for severe brain injury patients helps find proper treatments and reduce mortality.

摘要

我们分析了两组患者的治疗结果。第一组包括50例格拉斯哥昏迷评分(GCS)为3 - 8分的重型脑损伤患者,对其进行了持续颅内压(ICP)和脑灌注压(CPP)监测;第二组包括50例类似患者,未对其进行持续ICP监测。第一组中,8例患者的ICP正常(<2.0 kPa)、CPP正常(>9.33 kPa),其余42例患者的ICP升高且CPP降低。经过包括手术和药物治疗在内的充分干预后,第一组患者治疗效果良好,死亡率为14%。第二组患者基于临床观察接受了相同的干预,但治疗效果相对较差。我们认为,对重型脑损伤患者进行持续ICP和CPP监测有助于找到合适的治疗方法并降低死亡率。

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