Huang Y, Qian J, Lu R
Institute of Orthopaedics and Traumatology, Xijing Hospital, 4th Military Medical University, Xi'an, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 1998 Jan;12(1):1-4.
In order to investigate the effect of vascular beds on the vascular wall of autogenously grafted vein, femoral veins were reversely placed in between the cut ends of collateral femoral arteries in 11 dogs with atraumatic technique. The grafted veins were covered with vivid muscle or skin respectively after being assured to be patent, and investigated by histomorphologic method and computerized image analysis technique at postoperative intervals of 1 week, 4 weeks and 16 weeks. The results showed that: 1. One graft developed pseudoaneurysm at 1 week, and two grafts were occulded in skin-covered group, whereas, no complications occurred in muscle-covered group. 2. Intimal thickening of grafts in skin-covered group was much more obvious than that in the muscle-covered group (P < 0.05). 3. The relative contents of microstructural components of the graft wall showed no significant difference quantitatively between the two groups. So, the conclusion was: 1. Subcutaneous transplantation appeared to be a potential causative factor in inducing short-term excessive dilatation and long-term intimal hyperplasia of vein graft. 2. Muscular covering is of priority in blood vessel graft.
为研究血管床对自体移植静脉血管壁的影响，采用无创技术将11只犬的股静脉反向置于股侧副动脉断端之间。移植静脉在确认通畅后分别用肌肉或皮肤覆盖，于术后1周、4周和16周通过组织形态学方法和计算机图像分析技术进行观察。结果显示：1. 1周时1个移植物出现假性动脉瘤，皮肤覆盖组有2个移植物闭塞，而肌肉覆盖组未出现并发症。2. 皮肤覆盖组移植物内膜增厚比肌肉覆盖组明显得多（P<0.05）。3. 两组移植物壁微观结构成分的相对含量在数量上无显著差异。因此，结论为：1. 皮下移植似乎是导致静脉移植物短期过度扩张和长期内膜增生的一个潜在因素。2. 血管移植时优先选择肌肉覆盖。
