Gonçalves C E, Tokano-Ramos L V, Pasccoto R C, Bersani-Amado C A
Departamento de Odontologia, Universidade Estadual de Maringá.
Zhongguo Yao Li Xue Bao. 1998 Sep;19(5):422-4.
To evaluate the irritative potential of three dental bleaching agents (hydrogen oxide, carbopol, and carbamide peroxide).
In rats, Evans blue (2.5%, 1 mL.L-1) was injected i.v. and later each test solution was injected intradermally on the back. After the concentration of the dye in the stained skin area was determined by spectrophotometric analysis.
All the dental bleaching agents caused increase of vascular permeability and the intensity varied with the time.
Dental bleach agents had a great potential for irritating soft tissues.
评估三种牙齿漂白剂（过氧化氢、卡波姆和过氧化脲）的刺激潜力。
在大鼠中，静脉注射伊文思蓝（2.5%，1 mL·L-1），随后将每种测试溶液皮内注射到背部。通过分光光度分析测定染色皮肤区域中染料的浓度。
所有牙齿漂白剂均导致血管通透性增加，且强度随时间变化。
牙齿漂白剂对软组织有很大的刺激潜力。
