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激素替代疗法。适应症、益处及风险。

Hormone replacement therapy. Indications, benefits and risk.

作者信息

Davis S

机构信息

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne.

出版信息

Aust Fam Physician. 1999 May;28(5):437-45.

Abstract

BACKGROUND

The debate surrounding oestrogen replacement in peri and postmenopausal women has been made overly controversial by the dissemination of misinformation and subjective evaluation of available data both by proponents and opponents of such treatment.

OBJECTIVE

To review the indications, risks and benefits of oestrogen with and without progestin therapy in postmenopausal women.

CONCLUSIONS

When prescribed judiciously, such that undesirable side effects are avoided, many women well benefit overall from the use of oestrogen in the postmenopausal years. Clearly many of these benefits are long term in addition to providing acute symptomatic relief.

摘要

背景

关于围绝经期和绝经后女性雌激素替代治疗的争论,因支持和反对该治疗的各方传播错误信息以及对现有数据进行主观评估而变得过度有争议。

目的

回顾绝经后女性使用雌激素加或不加孕激素治疗的适应证、风险和益处。

结论

如果谨慎处方以避免不良副作用,许多女性在绝经后使用雌激素总体上会受益。显然,除了提供急性症状缓解外,这些益处中有许多是长期的。

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