Sørensen L C, Børch K
H:S Hvidovre Hospital, neonatalafdelingen.
Ugeskr Laeger. 1999 May 24;161(21):3094-8.
A retrospective study of a cohort of 54 term infants with perinatal asphyxia admitted to the neonatal intensive care unit at Hvidovre University Hospital i 1995 is described. The purpose of the study was to find clinical markers for prediction of outcome after perinatal asphyxia. Neither complications of pregnancy, gestational age, the sex of the infant, passage of meconium before delivery, abnormal fetal heart rate nor birth weight seemed to have any interrelationship with outcome. The Apgar score was more depressed, and the metabolic acidosis worse among the infants with poor outcome. The best predictor of outcome after intrapartum asphyxia was the severity of postasphyxial encephalopathy. No infant with mild or moderate postasphyxial encephalopathy died or developed any handicap. All with severe postasphyxial encephalopathy either died or developed minor handicaps.
本文描述了一项对1995年入住维德医院新生儿重症监护病房的54例足月围产期窒息婴儿队列的回顾性研究。该研究的目的是寻找预测围产期窒息后结局的临床指标。妊娠并发症、孕周、婴儿性别、分娩前胎粪排出、异常胎心或出生体重似乎均与结局无任何关联。结局不良的婴儿中,阿氏评分更低,代谢性酸中毒更严重。产时窒息后结局的最佳预测指标是窒息后脑病的严重程度。轻度或中度窒息后脑病的婴儿均无死亡或出现任何残疾。所有重度窒息后脑病的婴儿均死亡或出现轻度残疾。