Raoof S, Chowdhrey N, Raoof S, Feuerman M, King A, Sriraman R, Khan F A
Division of Pulmonary Diseases, Nassau County Medical Center, East Meadow, NY 11554, USA.
Chest. 1999 Jun;115(6):1658-66. doi: 10.1378/chest.115.6.1658.
Some critically ill patients have difficulty in mobilizing their respiratory secretions. These patients can develop pulmonary atelectasis that may result in hypoxemia. There are some data to show that atelectasis may be prevented by turning a patient from side to side utilizing special beds.
To determine the role of kinetic therapy (KT) combined with mechanical percussion (P) in the resolution of established atelectasis of the lungs and hypoxemia in critically ill, hospitalized patients. (KT was defined as rotation of a patient along the longitudinal axis of > or = 40 degrees to each side continuously.)
Prospective and randomized study (2:1 test to control group).
Twenty-four patients with respiratory failure, either mechanically ventilated or spontaneously breathing, who demonstrated segmental, lobar, or unilateral entire lung atelectasis were studied.
Medical ICU and adult respiratory ward in a county hospital in New York.
Seventeen patients were treated with KT combined with mechanical P using a KT system (Triadyne Kinetic Therapy System; KCI; San Antonio, TX). Seven patients received manual repositioning and manual P every 2 h. Both groups received similar conventional therapy with inhaled bronchodilators and suctioning.
Partial or complete resolution of atelectasis was seen in 14 of 17 patients (82.3%) in the test group as compared with 1 of 7 patient (14.3%) in the control group. The median duration to resolution of atelectasis was 4 days in the test group. Bronchoscopy was performed in 3 of 7 patients in the control group, but in none of the patients in the test group. A cost of $720 was incurred per patient for utilizing the specialty beds for a mean duration of 4 days. An improvement in oxygenation index occurred in the test group (change in baseline PaO2/fraction of inspired oxygen from 207.4+/-106.7 mm Hg to 318+/-100.7 mm Hg) at the end of therapy, while the control group showed a reduction over a similar duration of time (181.3+/-96.3 mm Hg to 112+/-21.2 mm Hg).
KT and mechanical P therapy resulted in significantly greater partial or complete resolution of atelectasis as compared with conventional therapy. There was a generalized trend toward statistical significance in the improvement of oxygenation and a reduced need for bronchoscopy in the group receiving KT and P therapy.
一些重症患者在排出呼吸道分泌物方面存在困难。这些患者可能会发生肺不张,进而导致低氧血症。有数据表明,使用特殊病床让患者翻身可预防肺不张。
确定动态治疗(KT)联合机械叩击(P)对重症住院患者已形成的肺不张和低氧血症的缓解作用。(KT定义为患者沿纵轴连续向两侧旋转≥40度。)
前瞻性随机研究(试验组与对照组比例为2:1)。
研究了24例呼吸衰竭患者,这些患者无论是机械通气还是自主呼吸,均表现为节段性、叶性或单侧全肺不张。
纽约一家县医院的内科重症监护病房和成人呼吸科病房。
17例患者使用KT系统(Triadyne动态治疗系统;KCI;得克萨斯州圣安东尼奥)接受KT联合机械叩击治疗。7例患者每2小时接受一次手动翻身和手动叩击。两组均接受类似的常规治疗,包括吸入支气管扩张剂和吸痰。
试验组17例患者中有14例(82.3%)肺不张部分或完全缓解,而对照组7例患者中仅有1例(14.3%)缓解。试验组肺不张缓解的中位时间为4天。对照组7例患者中有3例进行了支气管镜检查,而试验组无患者进行该项检查。使用专用病床平均4天,每位患者花费720美元。治疗结束时,试验组的氧合指数有所改善(基线动脉血氧分压/吸入氧分数从207.4±106.7 mmHg变为318±100.7 mmHg),而对照组在相似时间段内出现下降(从181.3±96.3 mmHg降至112±21.2 mmHg)。
与传统治疗相比,KT和机械叩击治疗能使肺不张更显著地部分或完全缓解。接受KT和叩击治疗的组在氧合改善方面有普遍的统计学显著趋势,且支气管镜检查需求减少。