Lecoules S, el Maghraoui A, Lapeyre E, Lechevalier D, Magnin J, Eulry F
Rheumatology Department, Bégin Armed Forces Instruction Hospital, Saint-Mandé, France.
Rev Rhum Engl Ed. 1999 May;66(5):292-5.
A 63-year-old man with strictly axial ankylosing spondylitis since the age of 28 years had a seven-year history of cystic seronegative rheumatoid arthritis with Felty's syndrome. Cysts were present in the hands, feet, wrists, shoulders, hips, one elbow, and one knee. There was no evidence of juxtaarticular demineralization, joint space loss, erosions, or joint destruction. Rheumatoid pannus was demonstrated within the cysts, particularly at the hip, ruling out cystic hip disease due to ankylosing spondylitis. HLA typing demonstrated the B27 and DR4 haplotypes. HLA B27 may be associated with a worse prognosis of rheumatoid hip involvement.
一名63岁男性，自28岁起患有严重的轴向型强直性脊柱炎，有7年的囊性血清阴性类风湿关节炎伴费尔蒂综合征病史。囊肿出现在手、足、腕、肩、髋、一个肘部和一个膝部。没有关节周围脱矿质、关节间隙变窄、侵蚀或关节破坏的证据。在囊肿内发现类风湿性血管翳，尤其是在髋部，排除了强直性脊柱炎所致的囊性髋关节疾病。HLA分型显示为B27和DR4单倍型。HLA B27可能与类风湿性髋部受累的预后较差有关。
