Mazza V, Contu G, Falcinelli C, Battafarano S, Cagnacci A, Vito G, Forabosco A, Volpe A
Department of Obstetric Science, Modena University, Italy.
Ultrasound Obstet Gynecol. 1999 May;13(5):308-11. doi: 10.1046/j.1469-0705.1999.13050308.x.
The aim of this study was to establish the biometric threshold of biparietal diameter (BPD), assumed to be an independent variable of gestational age, at which 100% accuracy in the assessment of fetal sex by ultrasonography is achievable.
Transvaginal and/or transabdominal sonography was used for detecting the 'sagittal sign' as a marker of fetal sex in 385 fetuses with BPD between 18 and 29 mm. The results of ultrasound examination were compared with sex at birth or with karyotype obtained from amniotic fluid cells or chorionic villus sampling.
Fetal sex assignment was feasible in 337 of 385 cases (87.5%). Of the 312 fetuses with known fetal sex outcome, 164 were males and 148 were females. An accuracy rate of 100% was achieved when a BPD of > or = 23 mm was obtained.
This study provides important information about the earliest stage of fetal development, expressed in terms of BPD, at which a diagnosis of fetal sex can be made with 100% accuracy.
本研究旨在确定双顶径（BPD）的生物测量阈值，将其假定为胎龄的一个独立变量，在该阈值下通过超声检查评估胎儿性别可达到100%的准确率。
对385例双顶径在18至29毫米之间的胎儿，采用经阴道和/或经腹超声检查来检测作为胎儿性别的标志物的“矢状征”。将超声检查结果与出生时的性别或从羊水细胞或绒毛取样获得的核型进行比较。
385例中有337例（87.5%）可行胎儿性别判定。在已知胎儿性别结果的312例胎儿中，164例为男性，148例为女性。当双顶径≥23毫米时，准确率达到100%。
本研究提供了关于胎儿发育最早阶段的重要信息，以双顶径表示，在这个阶段可以100%准确地诊断胎儿性别。
