de Grauw W J, van de Lisdonk E H, Behr R R, van Gerwen W H, van den Hoogen H J, van Weel C
Department of General Practice and Social Medicine, University of Nijmegen, The Netherlands.
Fam Pract. 1999 Apr;16(2):133-9. doi: 10.1093/fampra/16.2.133.
Traditionally, health and the outcomes of medical treatment have been measured in terms of morbidity, incidence or prevalence of disease, or even mortality. This disease model provides an adequate framework for acute illnesses, but for chronic diseases, severity and their effect on everyday functioning are paramount. For chronic diseases, functional health status, as a vital part of quality of life, is now recognized as an important outcome measure of the GP's care.
We aimed to assess the impact of type 2 diabetes mellitus on functional health status in Dutch general practice.
We conducted a cross-sectional study of the functional health status of all patients with type 2 diabetes mellitus under 85 in two general practices, using the Sickness Impact Profile (SIP) and the COOP/WONCA charts. A control group of non-diabetic patients was selected, matched for practice, sex and age.
In total, 127 type 2 diabetes mellitus patients and 127 controls participated in the study, the responses being 78 and 70%, respectively. Between these groups the following were significantly different: the SIP subscore Physical, the SIP sum score and the COOP/WONCA scores for physical fitness and overall health. Type 2 diabetes mellitus patients were 2.46 (95% CI 1.5-4.1) times more likely to experience functional impairment. Cardiovascular morbidity (odds ratio 2.5, 95% CI 1.3-4.7), locomotory morbidity (odds ratio 2.6, 95% CI 1.4-5.1) and diabetes itself (odds ratio 1.4, 95% CI 1.1-1.9) were significantly associated with the presence of functional impairment.
This study demonstrates the impact of type 2 diabetes mellitus on functional status, particularly in relation to cardiovascular morbidity.
传统上,健康及医疗治疗的结果一直是根据发病率、疾病发生率或患病率,甚至死亡率来衡量的。这种疾病模型为急性疾病提供了一个适当的框架,但对于慢性病来说,疾病严重程度及其对日常功能的影响才是至关重要的。对于慢性病,功能健康状况作为生活质量的一个重要部分,现在被认为是全科医生护理的一项重要结果指标。
我们旨在评估2型糖尿病对荷兰全科医疗中功能健康状况的影响。
我们使用疾病影响量表(SIP)和COOP/WONCA图表,对两家全科诊所中所有85岁以下的2型糖尿病患者的功能健康状况进行了横断面研究。选取了一个非糖尿病患者对照组,在诊所、性别和年龄方面进行了匹配。
共有127名2型糖尿病患者和127名对照者参与了研究,应答率分别为78%和70%。在这些组之间,以下方面存在显著差异:SIP身体亚评分、SIP总分以及COOP/WONCA身体适应能力和总体健康评分。2型糖尿病患者出现功能障碍的可能性高2.46倍(95%可信区间1.5 - 4.1)。心血管疾病(比值比2.5,95%可信区间1.3 - 4.7)、运动系统疾病(比值比2.6,95%可信区间1.4 - 5.1)以及糖尿病本身(比值比1.4,95%可信区间1.1 - 1.9)与功能障碍的存在显著相关。
本研究证明了2型糖尿病对功能状态的影响,尤其是与心血管疾病相关。