Elahi M M, Watkin K L, Hakim M S, Schloss M D, Lessard M L
Division of Plastic & Reconstructive Surgery, UCLA Medical Center, University of California, Los Angeles, USA.
Ann Plast Surg. 1999 Jun;42(6):651-7. doi: 10.1097/00000637-199906000-00012.
The objective of this study was to evaluate A-mode ultrasound in the assessment of cranial bone thickness utilizing an in vivo animal model. A prospective study was performed that identified four standardized calvarial points in 10 Landrace porcine skulls. The individual points were scanned with an A-mode ultrasonic transducer to obtain bone thickness measurements. The same points were measured subsequently using digital calipers for objective comparison. The accuracy of each of the measurement modalities was evaluated for inter- and intrarater reliability. The association between ultrasonic and caliper measurements was evaluated using Student's t-test, Pearson's correlation coefficient, and linear regression models to assess the effect of confounding variables. The mean difference between the ultrasonic and the caliper values was 0.31 +/- 0.22 mm (standard deviation). The statistical analyses employed strongly supported the predictive value of ultrasound as a function of the true calvarial thickness (p < 0.05, r > 0.88, R2 = 0.89). The results suggest that ultrasound is an accurate reflection of cranial bone thickness in an in vivo animal skull model. The development of a portable, noninvasive ultrasonic device can have substantial clinical implications for craniomaxillofacial surgery.
本研究的目的是利用活体动物模型评估A型超声在颅骨厚度评估中的应用。进行了一项前瞻性研究，在10个长白猪颅骨上确定了4个标准化的颅骨点。使用A型超声换能器对各个点进行扫描以获得骨厚度测量值。随后使用数字卡尺测量相同的点以进行客观比较。评估了每种测量方式在评估者间和评估者内可靠性方面的准确性。使用学生t检验、皮尔逊相关系数和线性回归模型评估超声测量值与卡尺测量值之间的关联，以评估混杂变量的影响。超声测量值与卡尺测量值之间的平均差异为0.31±0.22毫米（标准差）。所采用的统计分析有力地支持了超声作为真实颅骨厚度函数的预测价值（p<0.05，r>0.88，R2=0.89）。结果表明，在活体动物颅骨模型中，超声是颅骨厚度的准确反映。便携式、非侵入性超声设备的开发可能对颅颌面外科手术具有重大的临床意义。
