Kaiser B, Koene M, Swagemakers J, Bader H, Hoppen H O
Tierärztlichen Klinik für Pferde, Mühlen.
Tierarztl Prax Ausg G Grosstiere Nutztiere. 1999 May;27(3):180-6.
During the 1997 breeding season persistent follicles were diagnosed in 17 mares. In 16 of these mares a total of 17 follicles were transabdominally punctured and the steroids oestradiol, progesterone and testosterone were measured in the follicular fluid and in blood serum. In ten mares serving as a control group preovulatory follicles were punctured. The follicular fluid of the persistent follicles revealed a very high variability of the steroid concentrations. Depending on the steroid ratio within the follicles, eight follicles were rated as being intact, three follicles were undergoing atresia and five follicles were luteinized. Because of the high oestradiol levels of the follicular fluid within the control group, all of these follicles were considered to be intact. In both groups, no correlation of the steroid concentration between serum and follicular fluid was detectable. This fact argues against a passive diffusion of the steroids through the follicular wall. By puncturing the persistent follicles it was possible to bring the affected mares back into a physiological oestrus cycle within a normal dioestrus period.
在1997年繁殖季节,对17匹母马诊断出存在持久性卵泡。其中16匹母马的总共17个卵泡经腹穿刺,并对卵泡液和血清中的雌二醇、孕酮和睾酮等类固醇进行了测量。在作为对照组的10匹母马中,对排卵前卵泡进行了穿刺。持久性卵泡的卵泡液显示类固醇浓度具有很高的变异性。根据卵泡内的类固醇比例,8个卵泡被评定为完整,3个卵泡正在闭锁,5个卵泡已黄体化。由于对照组卵泡液中的雌二醇水平较高,所有这些卵泡都被认为是完整的。在两组中,均未检测到血清和卵泡液中类固醇浓度之间的相关性。这一事实表明类固醇并非通过卵泡壁被动扩散。通过穿刺持久性卵泡,有可能使受影响的母马在正常的间情期内恢复到生理性发情周期。