与华氏巨球蛋白血症相关的下颌骨淋巴肉瘤。
Lymphosarcoma of the mandible associated with macroglobulinemia of Waldenström.
作者信息
Shteyer A, Markitziu A
出版信息
Int J Oral Surg. 1978 Dec;7(6):585-9. doi: 10.1016/s0300-9785(78)80078-7.
PMID:103858
Abstract
Waldenström macroglobulinemia is a rare progressive immunoproliferative disorder involving lymphocytes and occasionally plasma cells. Unlike the multiple myeloma, this disease has minimal osseous lesions. Lesions in the jaws are very rare. This paper presents a case of lymphosarcoma in the mandible in a 68-year-old woman, who was diagnosed as suffering from Waldenström macroglobulinemia. The possibility of immunosuppression by Leukeran as an aetiologic factor causing the bone lesions is suggested.
摘要
华氏巨球蛋白血症是一种罕见的进行性免疫增殖性疾病，累及淋巴细胞，偶尔也累及浆细胞。与多发性骨髓瘤不同，这种疾病的骨病变极少。颌骨病变非常罕见。本文报告了一例68岁女性下颌骨淋巴肉瘤病例，该患者被诊断为患有华氏巨球蛋白血症。文中提出了苯丁酸氮芥免疫抑制作为导致骨病变的病因因素的可能性。
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