Friedlaender M H
Division of Ophthalmology, Scripps Clinic, La Jolla, CA 92037, USA.
Curr Opin Ophthalmol. 1998 Aug;9(4):54-8. doi: 10.1097/00055735-199808000-00010.
A wealth of antiallergic drugs is available for ocular allergy, and many new drugs will soon be approved. Pharmaceutical companies frequently seek approval of anti-inflammatory drugs for allergic indications, because it is relatively easy to perform clinical trials for ocular allergy. Extremely safe drugs for mild to moderate degrees of allergic conjunctivitis include antihistamines, mast cell stabilizers, and nonsteroidal anti-inflammatory agents. Topical corticosteroids, preferably those with reduced side effects, are available for more severe forms of ocular allergy. The choice of an antiallergic drug may be guided by the indication for which the drug was approved. The ultimate selection will be made based on the patient's symptoms, the drug's availability, and its cost.
有大量的抗组胺药物可用于眼部过敏,而且很快就会有许多新药获批。制药公司经常寻求将抗炎药物用于过敏适应症的批准,因为进行眼部过敏的临床试验相对容易。对于轻度至中度过敏性结膜炎,极其安全的药物包括抗组胺药、肥大细胞稳定剂和非甾体抗炎药。局部用皮质类固醇,最好是副作用较小的那些,可用于更严重的眼部过敏形式。抗组胺药物的选择可能以该药物获批的适应症为指导。最终的选择将基于患者的症状、药物的可获得性及其成本。