Tan Y K, da Silva A F
Department of Surgery, Wrexham Maelor Hospital NHS Trust, Croesnewydd Road, Wrexham, LL13 7TD, U.K.
Eur J Vasc Endovasc Surg. 1999 Jul;18(1):71-9. doi: 10.1053/ejvs.1999.0886.
to determine the role of digital photoplethysmography (D-PPG) in the diagnosis of deep-vein thrombosis (DVT), in comparison to the "gold standard" of either contrast ascending venography (ACV) or colour-flow duplex imaging (CFDI).
prospective study of 100 hospital inpatients (103 legs) referred to the X-ray department for ACV or CFDI with clinically suspected lower limb DVT in a district general hospital. Each patient was assessed by either ACV or CFDI, and D-PPG.
thirty-seven limbs were found to have DVT as demonstrated by ACV or CFDI. All patients with a venous refilling time (RT) of greater than 20 s and venous pump (VP) of greater than 35 had a normal ACV or CFDI. Using RT of less than 21 s as the optimal cut-off point, D-PPG achieved a sensitivity of 100%, negative-predictive value of 100%, specificity of 47% and positive-predictive value of 51%. By using VP of less than 36 as the optimal cut-off point, a sensitivity of 100%, a negative-predictive value of 100%, a specificity of 35% and positive-predictive value of 46% were achieved.
these results validate the use of portable D-PPG as a useful screening tool for the diagnosis of clinically suspected lower limb DVT. A positive test requires further confirmation by one of the "gold standard" methods, whereas a negative test effectively excludes DVT.
与对比剂上行静脉造影（ACV）或彩色血流双功成像（CFDI）这一“金标准”相比，确定数字光电容积脉搏波描记法（D-PPG）在诊断深静脉血栓形成（DVT）中的作用。
对一家地区综合医院因临床怀疑下肢深静脉血栓形成而被转诊至放射科进行ACV或CFDI检查的100例住院患者（103条腿）进行前瞻性研究。每位患者均接受ACV或CFDI以及D-PPG评估。
ACV或CFDI显示37条腿存在深静脉血栓形成。所有静脉充盈时间（RT）大于20秒且静脉泵（VP）大于35的患者ACV或CFDI结果均正常。以RT小于21秒作为最佳截断点时，D-PPG的灵敏度为100%，阴性预测值为100%，特异度为47%，阳性预测值为51%。以VP小于36作为最佳截断点时，灵敏度为100%，阴性预测值为100%，特异度为35%，阳性预测值为46%。
这些结果证实了便携式D-PPG可作为诊断临床怀疑下肢深静脉血栓形成的有用筛查工具。阳性检测结果需要通过一种“金标准”方法进一步确认，而阴性检测结果可有效排除深静脉血栓形成。
