The MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Sydney, Australia.
School of Engineering, Design and Built Environment, Western Sydney University, Sydney, Australia.
Sci Rep. 2024 Jan 15;14(1):1327. doi: 10.1038/s41598-023-50534-1.
Peripheral vascular diseases (PVDs) represent a significant burden on global human health and healthcare systems. With continued growth in obesity and diabetes, it is likely that the incidence of these conditions will increase. As many PVDs remain undiagnosed, low-cost and easy to use diagnostic methods are required. This work uses newly developed wearable electro-resistive morphic sensors to assess venous and arterial competence in the lower limbs of 36 healthy subjects. Comparison of this HeMo device was made to currently available benchtop light reflection rheography and photoplethymography devices. Results indicate that HeMo can detect the physiological signals of interest for both chronic venous insufficiency and peripheral arterial disease and all subjects were interpreted as healthy by each system. However, measurement repeatability of HeMo was highlighted as an issue that requires further system development. Furthermore, as HeMo captures changes in a section of limb circumference due to changes in underlying blood movement, rather than at a single point, the recorded signal is typically damped by comparison. This factor should be considered in any future developments.
外周血管疾病（PVD）给全球人类健康和医疗体系带来了巨大负担。随着肥胖症和糖尿病患者的不断增加，这些疾病的发病率可能会上升。由于许多 PVD 仍未被诊断出来，因此需要使用低成本且易于使用的诊断方法。本研究使用新开发的可穿戴式电阻式形态传感器来评估 36 名健康受试者下肢的静脉和动脉功能。将这种 HeMo 设备与现有的台式光反射容积描记法和光体积描记法设备进行了比较。结果表明，HeMo 可以检测到慢性静脉功能不全和外周动脉疾病的生理信号，并且每个系统都将所有受试者判断为健康。然而，HeMo 的测量重复性被认为是一个需要进一步系统开发的问题。此外，由于 HeMo 捕获的是由于血液流动变化导致肢体周长变化的信号，而不是单点信号，因此与单点信号相比，记录的信号通常会被衰减。在未来的任何开发中都应考虑这一因素。
